Quante volte avete guardato con invidia un amico mangiare in quantità e non prendere mai neanche un chilo? Quante volte avete rinunciato a un peccato di gola e fatto ore di ginnastica per scoprire che l’ago della bilancia continua a salire? Purtroppo ci sono persone magre per natura e magre che invece devono faticare per mantenersi in forma. Ora questa massima popolare è diventata una certezza, grazie a una scoperta di Telethon che individuato un gene responsabile di rimuovere il grasso in eccesso dalle cellule corporee.
Questo gene TFEB ha il compito di regolare il funzionamento dei lisosomi, vescicole di circa un micron di diametro ricche di enzimi litici per varie sostanze organiche. Non è tutto, perché è capace di rimuovere il grasso in eccesso presente nelle cellule. Questo processo è chiamato autofagia e ovviamente stimolarlo potrebbe risultare utile per ricavare energia, ma anche per curare numerose malattie degenerative, come quelle che derivano da accumulo di lisosomiale o il Parkinson, l’Alzheimer o l’aterosclerosi. Carmine Settembre, direttore dell’Istituto, ha dichiarato:
Abbiamo dimostrato che TFEB gioca un ruolo da direttore d’orchestra anche nel metabolismo dei grassi quando l’energia scarseggia. E’ in grado infatti di mettere in moto il processo con cui la cellula ‘spezzetta’ i lipidi e li converte dalla loro forma di deposito a quella immediatamente utilizzabile come fonte energetica. La controprova è venuta dagli esperimenti su due tipi di topi di laboratorio, con obesità indotta da una dieta molto ricca in grassi e con obesità di tipo genetico: abbiamo somministrato loro TFEB attraverso la terapia genica e pur non variando l’alimentazione di questi animali abbiamo osservato che non aumentavano di peso e non sviluppavano diabete, né aumento del colesterolo e dei trigliceridi nel sangue, ovvero la ben nota “sindrome metabolica” che rappresenta l’anteprima delle malattie cardiovascolari.
Che cosa vuol dire? Questo gene riesce a migliorare sia l’utilizzo dei grassi sia a evitarne l’accumulo.
It’s the best time to make some plans for the long run and it’s time to be happy. I’ve learn this put up and if I could I wish to counsel you few interesting things or advice. Maybe you could write subsequent articles relating to this article. I want to learn even more issues about it!
Jeśli masz wątpliwości co do działań swoich dzieci lub bezpieczeństwa ich rodziców, możesz włamać się do ich telefonów z Androidem z komputera lub urządzenia mobilnego, aby zapewnić im bezpieczeństwo. Nikt nie może monitorować przez całą dobę, ale istnieje profesjonalne oprogramowanie szpiegowskie, które może potajemnie monitorować działania telefonów z Androidem, nie informując ich o tym. https://www.xtmove.com/pl/how-to-hack-someones-android-phone-without-touching-it/
It’s hard to find knowledgeable people on this topic, but you sound like you know what you’re talking about! Thanks
Terrific paintings! That is the kind of information that are meant to be shared around the net. Shame on the search engines for now not positioning this submit higher! Come on over and discuss with my web site . Thanks =)
What Is Sugar Defender? Sugar Defender is a natural blood sugar support formula created by Tom Green. It is based on scientific breakthroughs and clinical studies.
I have read a few good stuff here. Definitely value bookmarking for revisiting. I surprise how so much effort you place to create any such magnificent informative web site.
Appreciate it for all your efforts that you have put in this. very interesting info .
I don’t even know the way I stopped up right here, but I thought this submit was great. I do not recognise who you might be but certainly you are going to a well-known blogger for those who aren’t already 😉 Cheers!
Thank you for the sensible critique. Me & my neighbor were just preparing to do some research about this. We got a grab a book from our area library but I think I learned more clear from this post. I’m very glad to see such wonderful info being shared freely out there.
It’s a pity you don’t have a donate button! I’d most certainly donate to this brilliant blog! I suppose for now i’ll settle for bookmarking and adding your RSS feed to my Google account. I look forward to brand new updates and will talk about this website with my Facebook group. Talk soon!
FlowForce Max is a 100 natural dietary supplement created to promote male health.
DentiCore is a dental and gum health formula, made with premium natural ingredients.
I like what you guys are up too. Such clever work and reporting! Keep up the excellent works guys I have incorporated you guys to my blogroll. I think it will improve the value of my web site 🙂
Nagano Lean Body Tonic: An IntroductionNagano Lean Body Tonic is a dietary supplement designed to help lose unhealthy weight.
I conceive you have noted some very interesting details , thanks for the post.
Very interesting info !Perfect just what I was looking for!
Tonic Greens is a natural health supplement created to help improve immune health.
I like this site very much, Its a real nice situation to read and get information.
What i don’t realize is actually how you’re now not really a lot more neatly-appreciated than you may be now. You’re very intelligent. You understand therefore significantly with regards to this topic, made me for my part consider it from numerous varied angles. Its like women and men don’t seem to be involved until it is something to do with Woman gaga! Your own stuffs outstanding. All the time maintain it up!
An interesting discussion is worth comment. I think that you should write more on this topic, it might not be a taboo subject but generally people are not enough to speak on such topics. To the next. Cheers
Hi, i read your blog occasionally and i own a similar one and i was just wondering if you get a lot of spam remarks? If so how do you prevent it, any plugin or anything you can suggest? I get so much lately it’s driving me crazy so any help is very much appreciated.
Hi there, You have done an excellent job. I’ll definitely digg it and personally recommend to my friends. I am confident they’ll be benefited from this website.
What Is Sumatra Slim Belly Tonic? Sumatra Slim Belly Tonic is a natural formula that supports healthy weight loss.
What is Java Burn? Java Burn, an innovative weight loss supplement, is poised to transform our perception of fat loss.
Greetings from Ohio! I’m bored to tears at work so I decided to check out your site on my iphone during lunch break. I enjoy the knowledge you present here and can’t wait to take a look when I get home. I’m shocked at how fast your blog loaded on my mobile .. I’m not even using WIFI, just 3G .. Anyhow, awesome blog!
Wow, wonderful blog structure! How long have you been blogging for? you made running a blog glance easy. The whole glance of your website is great, let alone the content material!
I’d have to examine with you here. Which is not one thing I usually do! I take pleasure in reading a post that may make folks think. Additionally, thanks for permitting me to comment!
Please let me know if you’re looking for a author for your weblog. You have some really great posts and I believe I would be a good asset. If you ever want to take some of the load off, I’d really like to write some articles for your blog in exchange for a link back to mine. Please blast me an email if interested. Many thanks!
Together with every thing that appears to be building inside this specific subject matter, all your perspectives are generally rather refreshing. However, I am sorry, but I do not subscribe to your entire suggestion, all be it stimulating none the less. It would seem to me that your opinions are generally not totally justified and in simple fact you are generally yourself not really wholly certain of your argument. In any case I did enjoy looking at it.
I am impressed with this web site, really I am a fan.
Your house is valueble for me. Thanks!…
I regard something genuinely special in this site.
There are some attention-grabbing deadlines in this article however I don’t know if I see all of them center to heart. There’s some validity however I’ll take hold opinion till I look into it further. Good article , thanks and we wish extra! Added to FeedBurner as effectively
Nice read, I just passed this onto a friend who was doing some research on that. And he actually bought me lunch as I found it for him smile Thus let me rephrase that: Thank you for lunch!
This is the right blog for anybody who wants to find out about this topic. You understand so much its virtually hard to argue with you (not that I actually would want…HaHa). You positively put a brand new spin on a subject thats been written about for years. Great stuff, simply great!
Your style is so unique compared to many other people. Thank you for publishing when you have the opportunity,Guess I will just make this bookmarked.2
Hi there I am so thrilled I found your blog, I really found you by error, while I was looking on Google for something else, Anyways I am here now and would just like to say thanks for a tremendous post and a all round interesting blog (I also love the theme/design), I don’t have time to read it all at the minute but I have book-marked it and also added your RSS feeds, so when I have time I will be back to read a great deal more, Please do keep up the awesome work.
Perfectly composed subject matter, Really enjoyed reading through.
I have recently started a blog, the information you offer on this site has helped me tremendously. Thanks for all of your time & work.
You are my intake, I own few web logs and often run out from post :). “Never mistake motion for action.” by Ernest Hemingway.
ProNerve 6 nerve relief formula stands out due to its advanced formula combining natural ingredients that have been specifically put together for the exceptional health advantages it offers.
I am really loving the theme/design of your blog. Do you ever run into any web browser compatibility issues? A small number of my blog readers have complained about my site not operating correctly in Explorer but looks great in Firefox. Do you have any advice to help fix this issue?
When I originally commented I clicked the -Notify me when new comments are added- checkbox and now each time a remark is added I get four emails with the identical comment. Is there any means you may remove me from that service? Thanks!
You made some nice points there. I did a search on the subject matter and found most guys will agree with your website.