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A seguito dei risultati ottenuti gli scienziati hanno potuto stabilire che l’assorbimento del colesterolo LDL variava in base alla dose di curcumina; esso, infatti, è stato ironicamente definito dai ricercatori dose-dipendente. Sottoporsi ad un trattamento con 100 uM di curcumina permette di inibire del 40% circa l’assorbimento del colesterolo LDL e di ridurre i livelli di alcune proteine, i cui nomi scientifici sono NPC1L1, NPC1L1 e mRNA. In conclusione, i ricercatori ritengono che la curcumina possa inibire in una quantità significativa l’assorbimento di colesterolo con una soppressione dell’espressione della NPC1L1 nelle cellule che costituiscono l’intestino.
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